PARP inhibitor Olaparib overcomes Sorafenib resistance through reshaping the pluripotent transcriptome in hepatocellular carcinoma

crystal beaded candle holder Abstract Hepatocellular carcinoma (HCC) is one of the most common human malignancies worldwide with very poor prognosis.Resistance to targeted therapeutic drugs such as sorafenib remains one of the major challenges in clinical treatment.In the present study, PARP1 was found to be highly expressed in human embryonic stem

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Estimating the effect of equipment reliability indices, schedules, and regular overhaul scopes on reliability and efficiency of combined heat and power plants

We have developed a technique and craggy range sauvignon blanc 2022 a programming-computing suite (PCS) to estimate the effect of equipment reliability indices, schedules, and regular overhaul scopes on reliability and efficiency of combined heat and power plants (CHPPs).We describe the approach to predict heat and electric loads for the investigat

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REGIONAL AUTHORS SELF-IDENTITY DEMONSTRATION IN MEMORIAL CONTEXTS

Purpose.The article is devoted to the pressing issue of regional identity preservation under conditions of linguoculturological globalization in modern society.The purpose of our research is to identify verbal means of expressing regional self-identification of narrators in the memorial context.The object is the self-identification of the narrator

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